Two fugitive animals travel across America in search of the ranch they once called home. Their journey becomes a test of their damaged friendship as they are pursued by an unusual pair of law-enforcement officers, including a DEA agent and a determined Fish and Wildlife ranger. What a super famous cast: Jakey Schiff as TBA, Emilio Iannucci as Thad, Kexin Wang as Cool Teen, Ryan Reynolds as Pony, Jason Momoa as Bear, Aubrey Plaza as TBA, Dan Levy as TBA, Eric André as TBA, Joaquim de Almeida as TBA, Ellie Bamber as TBA, Lil Rel Howery as TBA, Addison Rae as TBA, Luke Busey as Foal #1, Euan Macnaughton as Pilot, Peter Atencio as TBA, Brian Caspe as News Anchor, Nathan Cooper as Very Tall Passenger, Jimmy Smagula as Dave, Donald Sage Mackay as John Fitzgerald, Georgi S. Georgiev as Passenger, Kristi Kirilova as Passenger 6, Reis Daniel as Zane, JR Esposito as TSA Chief, Lucia Aliu as Diana, Owen Davis as Protester, Laura Fuino as Passenger #3, Valentina Kamenova as Passenger #2, John Riho Kim as Passenger, Ivan Rangelov as DEA Agent, John Harpley as Animal Rights Protester, Anwar Lynch as DEA Trainee #1, Peter Petrov-Pero as Ricardo, Zoë Anne Rinaldi as Goth Girl, Lily Hopwood as Young Patsy, Julianna Jennings as TV Reporter, Ginger Billy as Rick, Beatrice Baldwin as Protestor